apalutamide will lower the extent or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medication which might be CYP3A4 substrates can lead to decrease exposure to those remedies.bremelanotide will decrease the extent o